Introduction

vkdubey.bce@iitbhu.ac.in
0542-7165781
Dr. Vikash Kumar Dubey

Dr. Vikash Kumar Dubey

Professor (HAG)

School of Biochemical Engineering IIT (BHU)
0542-7165781
vkdubey.bce@iitbhu.ac.in

Research Interests

Cell Death Pathways and Diseases Protein Biochemistry Protein Engineering Biochemical Parasitology Isolation and Purification of Enzymes

Biography

Prof. Vikash Kumar Dubey has been a Full Professor since January 25, 2014. Before joining the Indian Institute of Technology (BHU), Varanasi in May 2018, he served at IIT Guwahati as Assistant Professor, Associate Professor, and later as Professor. Since July 1, 2020, he is Professor (HAG) at the School of Biochemical Engineering, IIT (BHU), Varanasi.

Over the years, he has demonstrated academic leadership, serving as Dean (Research & Development) at IIT (BHU) from January 1, 2022 to December 31, 2024, Coordinator/ Head of the School of Biochemical Engineering from February 2020 to February 2025, and Associate Dean (Academic Affairs) from June 2019 to February 2022. He also served as Project Director of the IDAPT-Foundation at IIT (BHU), under the National Mission on Cyber Physical Systems, from October 18, 2022 to June 2025. He is an active member of several national-level committees, expert panels, and faculty selection boards. At IIT Guwahati, he held several administrative roles, including Head, Centre for the Environment, Chairman of the Student Welfare Board, and Faculty-in-Charge. Prof. Dubey was a Postdoctoral Fellow at Florida State University, USA, from January 2004 to September 2006.

Professional Experience

July 2020 - Present Professor (HAG), School of Biochemical Engineering, IIT (BHU), Varanasi
Jan 2014 - Present Professor
Dec 2009 - Jan 2014 Associate Professor, IIT Guwahati
Sep 2006 - Nov 2009 Assistant Professor, IIT Guwahati
Jan 2004 - Sep 2006 Post-Doctoral Research Associate, Florida State University, USA

Membership of Scientific Societies

Fellow Memberships

  • Royal Society of Biology, United Kingdom (FRSB)
  • National Academy of Biological Sciences (FNABS)
  • Biotechnology Research Society of India (FBRS)
  • Association of Biotechnology and Pharmacy (FABAP)
  • Society of Applied Biotechnology (FSAB)

Life Memberships

  • The National Academy of Sciences, India
  • Biotechnology Research Society of India
  • Society of Biological Chemist (India)
  • Indian Science Congress Association
  • Epidemiological Foundation of India

Research Achievements

173+ Publications
7 US Patents
23 PhD Students
30+ M.Tech Students

Awards & Honors

Recognizing Excellence in Research and Academia

Major Awards

2025

Distinguished Professional AICTE

All India Council for Technical Education

2021

Best Teacher Award

IIT (BHU) Varanasi

2016

Prize for Biomedical Research in Underdeveloped Areas

Indian Council for Medical Research, Government of India

2012

B.M. Birla Science Prize in Biology

Birla Science Centre

Fellowships & Memberships

2018

Fellow, Royal Society of Biology (FRSB)

United Kingdom

2017

Vice President

Bioinformatics and Drug Discovery Society [BIDDS]

2014

Fellow, Biotech Research Society of India (FBRS)

For outstanding research in Medical Biotechnology

2013

Fellow, National Academy of Biological Sciences (FNABS)

Young Scientist Awards

2013

Extended Innovative Young Biotechnologist Award

DBT, Government of India

2010

Innovative Young Biotechnologist Award (IYBA-2009)

DBT, Government of India - Gold Medal & Citation

2012

Young Scientist Award

Society of Applied Biotechnology

2010

Young Scientist Award

Indian Society of Chemists and Biologists (ISCB)

Editorial Responsibilities

Associate Editor

  • PlosOne
  • Scientific Reports - Nature Publishing Group
  • Journal of Proteins and Proteomics - Springer
  • BMC Biotechnology (2014-2017)

Editorial Board Member

  • Protein and Peptide Letters - Bentham Science
  • ISRN Structural Biology - Hindawi
  • Cloning & Transgenesis - Omics Group
  • Advances in Natural and Applied Sciences

Editor & Reviewer

  • Biotechnology and Molecular Biology Reviews
  • Reviewer for ACS Biochemistry, Phytochemistry, PLOS journals
  • Publons Profile

Early Career Fellowships

Senior Research Fellowship

CSIR, Government of India

Training Fellowship

Instituto Pasteur-Foundazione Cenci Biolognetti, Rome, Italy

Junior Research Fellowship

CSIR, Government of India

CSIR-NET Qualified

National Eligibility Test for Research Fellowship & Lectureship

Publications

173+ Total Publications
2025 Latest Publication
H-Index High Impact

Recent Publications

2025

Investigating the function of UVRAG protein in regulation of apoptosis and autophagy and its implications in cancer

Shiv Kumar, Manash Sarma, Ehasanullah Khan and Vikash Kumar Dubey*

International Journal of Biological Macromolecules DOI: 10.1016/j.ijbiomac.2025.145847
2025

Development and evaluation of novel dual-target drugs encapsulated in liposome against visceral leishmaniasis

Kushal Bora, Shiv Kumar, Shankar Prasad Kanaujia, Vikash Kumar Dubey*

Journal of Drug Delivery Science and Technology DOI: 10.1016/j.jddst.2025.106883
2025

Targeting antioxidant defense system enzymes for Leishmaniasis treatment

Kushal Bora, Shankar Prasad Kanaujia, Vikash Kumar Dubey*

International Journal of Biological Macromolecules DOI: 10.1016/j.ijbiomac.2025.144650
2024

Molecular Mechanisms of Cell Death in Leishmania donovani Induced by Selected Steroidal Alkaloids

Naveena Menpadi, Pranjal Chandra, Vikash Kumar Dubey*

Journal of Basic Microbiology DOI: 10.1002/jobm.202400655

Publication Highlights

Most Cited

"Molecular docking studies of selected tricyclic and quinone derivatives on trypanothione reductase" - 150+ citations

High Impact

Publications in Nature, Elsevier, Wiley, and Springer journals with high impact factors

Collaborations

International collaborations with USA, Italy, and multiple Indian institutions

Top Publishing Journals

Elsevier Journals
45%
Wiley Journals
25%
Springer Journals
15%
Other Journals
15%

Explore Complete Publication Portfolio

Access all 173+ publications with detailed information and citations

View Full Publication List on IRINS

Book Chapters & Academic Contributions

7+ Book Chapters
40 NPTEL Lectures
1 Database

Published Book Chapters

S.No. Author/Co-authors/Editor Year Title of Book(s)/Book Chapters Details of Publisher
1 Timir Tripathi, Vikash Dubey 2022 Advances in Protein Molecular and Structural Biology Methods 1st Edition - January 14, 2022 (Book) Elsevier
2 Gundappa Saha, Sukanya Ghosh, Vikash Kumar Dubey, Prakash Saudagar 2022 Gene Alterations Induced by Glutamine (Q) Encoding CAG Repeats Associated with Neurodegeneration.
In: Pereira, G.C. (eds) Gene, Drug, and Tissue Engineering. Methods in Molecular Biology, vol 2575.
Humana, New York, NY
Online ISBN: 978-1-0716-2716-7
3 Shyamali Sarma, Vikash Kumar Dubey, Vijayanand S. Moholkar 2022 Chapter 16 - Circular bioeconomy for biodiesel industry: Upgradation of waste glycerol to value-added products.
Editor(s): Sunita Varjani, Ashok Pandey, Thallada Bhaskar, S. Venkata Mohan, Daniel C.W. Tsang, Biomass, Biofuels, Biochemicals, Pages 419-438.
DOI: 10.1016/B978-0-323-89855-3.00017-0
Elsevier
ISBN: 9780323898553
4 Gundappa Saha, Prakash Saudagar and Vikash Kumar Dubey 2019 Virus like particles: nano-carriers in targeted therapeutics.
In: Encapsulation of Active Molecule and their Delivery systems.
Elsevier
ISBN: 978-0-12-819363-1
5 Bishal Kumar Singh and Vikash Kumar Dubey 2014 Leishmaniasis: Trypanothione metabolism as potential drug targets for rational drug designing (Chapter 20).
In Recent Developments in Biotechnology (J.N. Govil Ed). Vol 9; pp 455-471.
Studium Press LLC, USA
ISBN: 1-62699-024-7
6 Vikash Kumar Dubey and Suman Kundu 2014 Processing of Recombinant Proteins (Chapter 34).
In Gene and its Engineering. H. K. Das.Ed
Wiley
ISBN: 978-81-265-4928-3
7 Ritesh Kumar, Shalini Singh and Vikash Kumar Dubey 2015 Bioinformatics Tools to Analyze Proteome and Genome Data.
In: Advances in the Understanding of Biological Sciences Using Next Generation Sequencing (NGS) Approaches.
Editors: Sablok, G., Kumar, S., Ueno, S., Kuo, J., Varotto, C. Page 179-194.
Springer
ISBN: 978-3-319-17157-9

Additional Academic Contributions

NPTEL Online Course

Prepared 40 lectures for National Program for Enhanced Learning (NPTEL), an initiative of IITs and IISc funded by MHRD

Research Database

Developed and maintained a comprehensive research database for academic and research purposes

Published With

Elsevier
Springer
Wiley
Humana
Studium Press

Patents & Intellectual Property

12+ Total Patents
7 US Patents
5 Indian Patents

Patent Portfolio

Year Title International/National Status Patent/Application No.
2025 A drug Delivery Vehicle and a method of preparation thereof National Filed 202511001317
2025 An anti-parasitic composition for the management of Leishmaniasis
Vikash Kumar Dubey, Kushal Bora
National Awarded 202411054976
Patent No.: 573209
2024 A thrombin receptor antagonist for management of leishmaniasis
Vikash Kumar Dubey, Preeti Ranjan
National Awarded 202211067169
Patent No.: 564781
2022 An Anti-Leishmanial Steroidal Alkaloid Drug Compound National Published 202211049337
2013 Oxabicyclo derivatives as novel antileishmanial compound National Published — Award Pending 63/KOL/2013
2012 Mutants of human fibroblast growth factor having increased stability and/or mitogenic potency International (US Patent) Awarded 8,119,776
2012 Mutants of human fibroblast growth factor having increased stability and/or mitogenic potency International (US Patent) Awarded 8,153,770
2012 Mutants of human fibroblast growth factor having increased stability and/or mitogenic potency International (US Patent) Awarded 8,153,771
2010 Iridoid glucosides from Nyctanthes arbortristis as new inhibitor of Trypanothion reductase National Pending 306/KOL/2010
2010 Mutants of human fibroblast growth factor having increased stability and/or mitogenic potency International (US Patent) Awarded 7,659,379
2009 A novel cysteine protease, procerain B, from Calotropis procera National Pending 1346/KOL/2009
2009 Mutant polypeptides of Fibroblast Growth Factor-1 International (US Patent) Awarded 7,595,296
2010 Mutant polypeptides of Fibroblast Growth Factor-1 International (US Patent) Awarded 7,696,171
2010 Mutant polypeptides of Fibroblast Growth Factor-1 International (US Patent) Awarded 7,776,825

Patent Statistics

Awarded Patents

9

Successfully granted patents

Pending Patents

3

Under examination process

US Patents

7

International patent grants

Indian Patents

5

National patent filings

Research Focus Areas

Leishmaniasis Treatment

Anti-parasitic compositions and drug compounds for managing leishmaniasis

Protein Engineering

Mutant polypeptides and growth factors with enhanced stability

Drug Delivery Systems

Innovative drug delivery vehicles and methods

Natural Products

Novel compounds from natural sources for therapeutic applications

Dean (Research & Development)
IIT (BHU) Varanasi 2022-2024
Coordinator/Head, School of Biochemical Engineering
IIT (BHU) Varanasi 2020-2025
Associate Dean (Academic Affairs)
IIT (BHU) Varanasi 2019-2022
Project Director, IDAPT-Foundation
IIT (BHU) Varanasi 2022-2025
Head, Centre for the Environment
IIT Guwahati 2015-2018
Chairman, Student Welfare Board
IIT Guwahati 2014-2016
Member, Board of Governors
IIT (BHU) Varanasi 2022-2023
Chairman, Institute Ranking Committee
IIT (BHU) Varanasi 2022-2024
Coordinator IPR (I/C)
IIT (BHU) Varanasi 2022-2024

Human IL-2 fused leishmanial trypanothione synthetase (TS) as protein vaccine candidates

Development of novel vaccine candidates against leishmaniasis using trypanothione synthetase fused with human IL-2.

Funding: ICMR 2021-2025

How Beclin 1 mediates cross-talk between apoptosis and autophagy via its C-terminal fragment?

Investigating the molecular mechanisms of Beclin 1 in regulating cross-talk between apoptosis and autophagy pathways.

Funding: CSIR 2019-2023

Validation of glutathione synthetase from Leishmania donovani as new drug target

Identification and validation of glutathione synthetase as a potential drug target for anti-leishmanial drug development

Funding: ICMR 2021-2024

Integrated computational and experimental studies to potential therapy of kala-azar

Targeting Dephosphocoenzyme A Kinase (LdDPCK) of the pathogen as a target for leishmaniasis treatment

Funding: IDAPT Hub 2021-2025

Re-purposing of approved drugs for COVID-19 treatment

Targeting SARS-CoV-2 main protease using drug repurposing approach for potential COVID-19 therapeutics.

Funding: SERB 2020-2021

Metabolic engineering of rapid-growing cyanobacteria for farnesene production

Engineering cyanobacteria for sustainable production of farnesene and scale-up studies.

Funding: SERB 2023-2026

Ms. Naveena Menpadi

PhD Student

Studies on anti-leishmanial Compound Discovery

Mr. Kushal Bora

Joint PhD Student

Joint PhD with IIT Guwahati

Mr. Shiv Kumar

PhD Student

Research on apoptosis and autophagy

Ms. Atreyee Chatterjee

PhD Student

Biochemical research

Ms. Ankita Mondal

PhD Student

Molecular biology studies

Mr. Abhinav Kant

PhD Student

Protein engineering research

Ms. Shumaila Rashid Sheikh

Joint PhD Student

Joint PhD with IIT Guwahati

Lab Alumni

The research group has successfully supervised 23 Ph.D. students (awarded), 30 M.Tech. students (including final-year IDD theses), and has mentored several postdoctoral researchers, project fellows, and trainees.

Recent PhD Graduates:

  • Dr. Preeti Ranjan (2024) - Prime Minister Fellowship recipient
  • Dr. Kumari Prerna (2023) - Currently Postdoctoral researcher at University of Pennsylvania, USA
  • Dr. Debanjan Kundu (2022) - Currently Assistant Professor, SRM University, Chennai
  • Dr. Rahul Kumar (2022) - Currently Assistant Professor, Government of Bihar
  • Dr. Gundappa Saha (2020) - Currently Postdoctoral Researcher, University of Pennsylvania, USA

Events

Event Title Venue Date
Drug Discovery and Translational Healthcare 2025 (DDTH 2025) IIT (BHU) Varanasi December 2–3, 2025
Smart India Hackathon 2022 IIT (BHU) Varanasi Nodal Centre August 25–26, 2022
Short-term Course on Computer Aided Drug Design and Protein Analysis IIT (BHU) Varanasi February 22–26, 2021
National Conference on Computational and Biochemical Drug Discovery (NCCBDD-2021) IIT (BHU) Varanasi September 11–12, 2021
Recent Advancements in Biochemical Engineering and Biotechnology IIT (BHU) Varanasi March 15–16, 2019
Recent Developments in Medical Biotechnology and Structure-Based Drug Designing IIT Guwahati December 6–7, 2015
Conference on Bioinformatics and Computer Aided Drug Design (CBCADD 2015) IIT Guwahati December 7, 2015
Symposium cum Workshop on Advances in Computational Biology and Computer Aided Drug Design IIT Guwahati June 24–26, 2015

Invited Talks

Talk Title Event / Institution Date
Development of novel dual-target drugs against visceral leishmaniasis and combinational study with miltefosine Drug Discovery 2025: Emerging Trends and Future Prospects February 2025
Immunoinformatic approach to design of novel multi-epitope vaccines against Leishmania 9th International Conference on Current Trends in Drug Discovery Research February 2025
Entrepreneurship Crossroads: How to conquer the big Sharks! Faculty of Commerce, Banaras Hindu University April 2025
Unveiling the Secrets of Leishmania Infection: A Deep Dive into Its Mysterious Realm Department of Biochemical Engineering, HBTU Kanpur April 2025
Exploring Biochemical pathways for Drug discovery Berhampur University January 2025
Exploring the Mysterious Realm of Leishmania Infection Conference on Structural Biology and Drug Discovery, SRM Chennai October 2024
Navigating the Enigmatic World of Leishmania Infection ETMM 2024: Emerging Technologies and Materials in Medicine, IIT Kanpur May 2024
Concepts in circular dichroism DST STUTI training program, SATHI BHU June 2023
Protein Engineering approaches for various Biomedical Applications Workshop on Phylogenomics and Network Biology, NCCS Pune March 2023
Leishmania research: Promising Biochemical and Immunological results provides hope for the future 91st Annual Session & Symposium, The National Academy of Sciences December 2021